NOAC Dose Calculator
for SPAF

NOAC dose calculator

NOAC calculator for VTE/PE

Age

Body weight

Serum creatinine

Sex

Drugs

Liver disease

male

female

None

Any of this ( dronedarone, ciclosporin, erythromycin, or ketoconazole)

None

yes

Child-Pugh score

Encephalopathy

No

Grade 1-2

Grade 3-4

Ascites

No

Mild

Moderate

Bilirubin

<2 mg/dl (<34 umol/L)

2-3 mg/dl (34-50 umol/L))

>3 mg/dl (>50 umol/L)

Albumin

>3.5 g/dL (>35 g/L)

2.8-3.5 g/dL (28-35 g/L)

<2.8 g/dL (<28 g/L)

INR

<1.7

1.7-2.3

>2.3

Submit

Age ≥ 80 yr. (A, D)

BW ≤ 60 kg. (A, E)

Cr ≥ 1.5 mg/dl (A)

or ≥ 133 μmol/l

CrCl 15- 50 ml/min (R, E)

CrCl 15- 30 ml/min (A)

CrCl, ml/min

Dabigatran

-

Rivaroxaban

-

Apixaban

-

Edoxaban

-

ELDERCARE-AF: Edoxaban 15 mg daily

Eligibility Criteria:

CHADS2 score of 2 or higher.

Inappropriate candidates for oral anticoagulants at the recommended therapeutic strength

or at approved doses for one or more of the following reasons

A low creatinine clearance (15 to 30 ml per minute)
A history of bleeding from a critical area or organ or gastrointestinal bleeding
Low body weight (≤45 kg)
Continuous use of nonsteroidal antiinflammatory drugs (NSAIDs), or current use of an antiplatelet drug.

How does the NOAC dose calculator work?

References

Steffel J, Collins R, Antz M, Cornu P, Desteghe L, Haeusler KG, Oldgren J, Reinecke H, Roldan-Schilling V, Rowell N, Sinnaeve P, Vanassche T, Potpara T, Camm AJ, Heidbüchel H; External reviewers. 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation. Europace. 2021 Oct 9;23(10):1612-1676.

Your Feedback Matters

We're committed to providing accurate and efficient tools for clinical decision-making. If you have suggestions or encounter any issues with this medical calculator, we’d greatly appreciate your feedback. Your insights help us improve usability and clinical relevance.