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Fluconazole
CrCl
(ml/min)
>50
≤50
Intermittent HD
CRRT
CAPD
Fluconazole
200-400 mg IV/PO post HD
alt: 200-400 mgx1 then 100-200 mg IV/PO q 24 h
100-200 mg IV/PO q 24 h
200-400 mg IV/PO q 24 h
Load 800 mgx1 then
400 mg IV/PO q 24 h
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Conditions | Dose |
|---|---|
CrCl ≥ 50 ml/min | 200 - 400 mg IV/PO Q24H |
CrCl < 50 ml/min | 100 - 200 mg IV/PO Q24H |
Hemodialysis | 200 - 400 mg IV/PO post-HD |
alt: 200 - 400 mg x 1, then 100 - 200mg IV/PO Q24H | |
CAPD | 50 - 200 mg q24h |
CRRT | Load 800 mg x 1 dose, then 400mg IV/PO Q24H |
SLED | 800 mg initial dose, then 400 mg q12h (or pre/post SLED) |
Give initial dose at start of an 8-hr dialysis sesstion, or 16-hr before the next session. |
Conditions | Dose |
|---|---|
CrCl ≥ 50 ml/min | Load 800 mg x 1 dose, then 400 - 800 mg IV/PO Q24H |
CrCl < 50 ml/min | Load 800 mg x 1 dose, then 200 - 400 mg IV/PO Q24H |
Hemodialysis | Load 800 mg x 1 dose, then 400 - 800 mg post-HD |
alt: 200 - 400 mg IV/PO Q24H | |
CAPD | 50 - 200 mg q24h |
CRRT | Load 800 mg x 1 dose, then 400 - 800 mg IV/PO Q24H |
SLED | 800 mg initial dose, then 400 mg q12h (or pre/post SLED) |
Give initial dose at start of an 8-hr dialysis sesstion, or 16-hr before the next session. |
Conditions | Dose |
|---|---|
CrCl ≥ 50 ml/min | 800 mg IV/PO Q24H |
CrCl < 50 ml/min | Load 800 mg x 1 dose, then 400 mg IV/PO Q24H |
Hemodialysis | 800 mg post-HD |
alt: 800 mg x 1, then 400 mg IV/PO Q24H | |
CAPD | 50 - 200 mg q24h |
CRRT | 800 mg IV/PO Q24H |
SLED | 800 mg initial dose, then 400 mg q12h (or pre/post SLED) |
Give initial dose at start of an 8-hr dialysis sesstion, or 16-hr before the next session. |
The Cockcroft-Gault equation may yield inaccurate estimates based on a patient's body weight and BMI. By including additional height information, we can calculate BMI and provide a modified estimate and range.
- Underweight: For a BMI of 18.5 or lower, use the actual body weight for calculations.
- Normal Weight: Use the ideal body weight for calculations.
- Overweight/Obese: For a BMI of 25 or higher, use the adjusted body weight for calculations.
Calculation Steps
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