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Aortic regurgitation

Echocardiographic assessment of aortic regurgitation grade

Parameters

mild AR

moderate AR

severe AR

Structural parameters

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Aortic leaflets

Normal or abnormal

Normal or abnormal

Abnormal/flail, or wide coaptation defect

LV size

Normal*

Normal or dilated

Usually dilated†

Qualitative Doppler

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Jet width in LVOT, color flow

Small in central jets

Intermediate

Large in central jets; variable in eccentric jets

Flow convergence, color flow

None or very small

Intermediate

Large

Jet density, CW

Incomplete or faint

Dense

Dense

Jet deceleration rate, CW (PHT, msec)‡

Slow, >500

Medium, 500-200

Steep, <200

Diastolic flow reversal in descending aorta, PW

Brief, early diastolic reversal

Intermediate

Prominent holodiastolic reversal

Semiquantitative parameters§

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VCW (cm)

<0.3

0.3-0.6

>0.6

Jet width/LVOT width, central jets (%)

<25

25-45            46-64

≥65

Jet CSA/LVOT CSA, central jets (%)

<5

5-20            21-59

≥60

Quantitative parameters§

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RVol (mL/beat)

<30

30-44            45-59

≥60

RF (%)

<30

30-39            40-49

≥50

EROA (cm²)

<0.10

0.10-0.19            0.20-0.29

≥0.30

PHT, Pressure half-time; PW, pulsed wave Doppler. Bolded qualitative and semiquantitative signs are considered specific for their AR grade. Color Doppler is usually performed at a Nyquist limit of 50-70 cm/sec.

*Unless there are other reasons for LV dilation.

† Specific in normal LV function, in the absence of causes of volume overload. Exception: acute AR, in which chambers have not had time to dilate.

‡ PHT is shortened with increasing LV diastolic pressure and may be lengthened in chronic adaptation to severe AR.

§ Quantitative parameters can subclassify the moderate regurgitation group.

References

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1) Zoghbi, W.A., Adams, D., Bonow, R.O., Enriquez-Sarano, M., Foster, E., Grayburn, P.A., Hahn, R.T., Han, Y., Hung, J.W., Lang, R.M., Little, S.H., Shah, D.J., Shernan, S.K., Thavendiranathan, P., Thomas, J., & Weissman, N. (2017). Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation: A Report from the American Society of Echocardiography Developed in Collaboration with the Society for Cardiovascular Magnetic Resonance. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 30 4, 303-371 .

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