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Ceftazidime
Normal Dose
(Full dose)
1 g q 8 h (Severe infection 2 g q 8 h)
CrCl
(ml/min)
>50
31-50
16-30
Intermittent HD
CRRT
Ceftazidime
1-2 g q 24 h
1-2 g q 12 h
1-2 g IV q 8 h
6-15
0.5-1 g q 24 h
<5
0.5 g q 24 h
0.5-1 g q 24 h
(dose daily but after dialysis on dialysis day)
2 g load then
1 g q 8 h or
2g q 12 h
CAPD
Conditions | Dose |
|---|---|
CrCl > 50 ml/min | 1 - 2 g IV q8h |
CrCl 30 - 50 ml/min | 1 - 2 g IV q12h |
CrCl 16 - 30 ml/min | 1 - 2 g IV q24h |
CrCl 6 - 15 ml/min | 0.5 - 1 g IV q24h |
CrCl < 6 ml/min | 0.5 g IV q24h |
Hemodialysis | 0.5 - 1 g IV q24h |
Dose daily, but after HD on HD days | |
CAPD | No data |
CRRT | 2 g IV load, then 1 g IV q8h |
SLED | 1 gm q 12h |
The Cockcroft-Gault equation may yield inaccurate estimates based on a patient's body weight and BMI. By including additional height information, we can calculate BMI and provide a modified estimate and range.
- Underweight: For a BMI of 18.5 or less, use the actual body weight for calculations.
- Normal Weight: Use the ideal body weight for calculations.
- Overweight/Obese: For a BMI of 25 or higher, use the adjusted body weight for calculations.
Calculation Steps
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