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Cefepime
Last patient
Height
Age
Serum Creatinine
CrCl (ml/min) by IBW
Body weight
Sex
*
Male
Female
CrCl (ml/min) by true BW
CrCl (ml/min) by Adjusted BW
Normal Dose
(Full dose)
1-2 gm q 8 h
General
Pulmonary/Febrile Neutropenia/CNS/Pseudomonal infection/Severe infection
Extend infusion: 4 h infusion
CrCl
(ml/min)
>60
30-60
11-29
Intermittent HD
CRRT
CAPD
Cefepime
0.5-1 g q 24 h
dose daily but after dialysis on dialysis day
1 g q 24 h
1 g q 12 h or
2 g q 24 h
1 g q 8 h or
2 g q 12 h
2 g load then
1 g q 8 h
<10
500 mg q 24 h
Extend infusion: 4 h infusion
CrCl
(ml/min)
Intermittent HD
CRRT
CAPD
Cefepime
0.5-1 g q 24 h
dose daily but after dialysis on dialysis day
2 g load then
1 g q 8 h
>60
30-60
11-29
1 g q 12 h
2 g q 12 h
2 g q 8 h
<10
1 g q 24 h
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