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Amikacin

Sex

CrCl
(ml/min)

>60

40-59

30-39

Intermittent HD

CRRT

CAPD

Amikacin

Not recommended

15 mg/kg q 48 h

15 mg/kg q 36 h
 

15-20 mg/kg q 24 h

Not recommended

??

<30

Not recommended

Contraindications for High-Dose Extended-Interval Dosing: Pregnancy, Burn > 20%BSA, Large ascites, endocarditis (Please use conventional dosing.)

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