Fluconazole

Height

Age

Serum Creatinine

CrCl (ml/min) by IBW

Body weight

Sex

Male

Female

CrCl (ml/min) by true BW

CrCl (ml/min) by Adjusted BW

CrCl
(ml/min)

>50

≤50

Intermittent HD

CRRT

CAPD

Fluconazole

200-400 mg IV/PO post HD
alt: 200-400 mgx1 then 100-200 mg IV/PO q 24 h

100-200 mg IV/PO q 24 h

200-400 mg IV/PO q 24 h

Load 800 mgx1 then
400 mg IV/PO q 24 h

??

Fluconazole

CrCl
(ml/min)

>50

≤50

Intermittent HD

CRRT

CAPD

Fluconazole

200-400 mg IV/PO post HD
alt: 200-400 mgx1 then 100-200 mg IV/PO q 24 h

100-200 mg IV/PO q 24 h

200-400 mg IV/PO q 24 h

Load 800 mgx1 then
400 mg IV/PO q 24 h

??

CrCl
(ml/min)

>50

Intermittent HD

CRRT

CAPD

Fluconazole

Load 800 mgx1 dose
then 400-800 mg post HD
alt: 200-400 mg IV/PO q 24 h

Load: 800 mgx1 then
400-800 mg IIV/PO q 24 h

Load 800 mgx1
then 400-800 mg IV/PO q 24 h

≤50

Load 800 mgx1
then 200-400 mg IV/PO q 24 h

??

CrCl
(ml/min)

>50

Intermittent HD

CRRT

CAPD

Fluconazole

800 mg post HD
alt: 800 mgx1 then
400 mgIV/PO q 24 h

800 mg IIV/PO q 24 h

800 mg IV/PO q 24 h

≤50

Load 800 mgx1
then 400 mg IV/PO q 24 h

??

Fluconazole

CrCl (ml/min)

>50

≤50

Intermittent HD

CRRT

CAPD

Fluconazole

200-400 mg IV/PO post HD alt: 200-400 mgx1 then 100-200 mg IV/PO q 24 h

100-200 mg IV/PO q 24 h

200-400 mg IV/PO q 24 h

Load 800 mgx1 then 400 mg IV/PO q 24 h

??

CrCl
(ml/min)

200-400 mg IV/PO post HD
alt: 200-400 mgx1 then 100-200 mg IV/PO q 24 h

Load 800 mgx1 then
400 mg IV/PO q 24 h