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Ceftazidime/Avibactam
Normal Dose
(Full dose)
2.5 g q 8 h
CrCl
(ml/min)
>51
31-50
16-30
Intermittent HD
CRRT
Ceftazidime/
Avibactam
750 mg/187.5 mg
q 12 h
1 g/0.25 g q 8 h
2.5 g IV q 8 h
in 2 h
6-15
750 mg/187.5 mg
q 24 h
<6
750 mg/187.5 mg
q 48 h
750 mg/187.5 mg
q 48 h (after dialysis on HD day)
1 g/0.25 g q 8 h
(2.5 g q 8 h
if MIC>4 mcg/ml)
CAPD
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