Midazolam
Max concentration : Undiluted (5 mg/ml)
Solution: NSS, D5W
Dosing instruction: Bolus Dose 0.03-0.3 mg/kg (0.5-4 mg)
Infusion rate: 0.02-0.2 mg/kg/min
Titrate dose by 1 mg/h to achieve desired effect
Body Weight
kg.
Midazolam 20mg/100ml (0.2 mg/ml)
Rate (ml/hr)
Midazolam 50mg/100ml (0.5 mg/ml)
Rate (ml/hr)
Dose (mg/kg/h)
Richmond Agitation-Sedation Scale (RASS)
RASS score
RASS scoring and interpretation should be based on the sedation protocol being used. For minimal sedation protocols (RASS -2 to 0), sedation should be modified or decreased for a RASS score of -3 or less.
+4 Combative, violent, danger to staff
+3 Pulls or removes tube(s) or catheters; aggressive
+2 Frequent non-purposeful movement, fights ventilator
+1 Anxious, apprehensive, but not aggressive
0 Alert and calm
-1 Awakens to voice (eye opening/contact) > 10 seconds
-2 Light sedation; briefly awakens to voice (eye opening/contant) < 10 seconds
-3 Moderate sedation; movement or eye opening. No eye contact
-4 Deep sedation; no response to voice, but movement or eye opening to physical stimulation
-5 Unarousable; no response to voice or physical stimulation
Voice